My defensive strategy would be to play as much full court pressure as possible. However, at all times, make sure McDermott doesn't beat us from the perimiter. I would rather have him posting up someone like Dom or Sampson as long as O'Bekpa is in the game to swat some post up shots.
In addition, my offensive strategy would be to focus on whatever man he is covering. That player would be the guy that I would use to be the main point of the offense. For instance, if he is guarding Sampson, have Jordan or Branch dump it down low to him. Try to get him into foul trouble early.